India-based Miraqules developed a nanotechnology that mimics blood clotting proteins to quickly stop heavy bleeding.

When Demetri Maxim was seven years old, his mother’s kidneys stopped working. She was put on dialysis, which meant that she had to go to the hospital four times a week to have her blood filtered by a machine since her own kidneys could no longer function independently. Two years later, Maxim’s mother received a [...]

Large enterprises routinely buy more electricity than they use. COI Energy has a patented platform that lets them sell and share.

The company's so-called Pathfinder software can look at almost anything — buildings, tree-lined roads, even aerial views — and quickly match it to a database and generate real-time navigation.

Spaceship has hit 5Million domains under management and released a recent trends breakdown. com vs. all other TLD registrations Only 17% of registrations are .com, compared to all other TLDs, which represent 83%. When we hit 1 million domains under management, .com accounted for 13% of registrations. While there’s been a slight increase, it still [...]

.CV has been doing more in 2025 to increase their visibility. They only have a couple reported domain sales at Namebio. Ai.Cv sold for $20,000 at the end of 2024. I interviewed Opeyemi Awoyemi and I was surprised to see that after being used for personal resume sites, another angle is CV being used for [...]

Today is the first day of TechCrunch Disrupt 2025, where 10,000 founders, investors, and builders are flooding Moscone West for a nonstop run of ideas, demos, and deals. The energy is electric, the conversations are everywhere, and the breakthroughs are only just beginning. Don't miss out. Register here or head straight to Moscone West to [...]

Onfire, a vertical AI platform for IT revenue teams, is coming out of stealth with $20 million in funding, including a $14 million Series A co-led by Grove Ventures and TLV Partners.

Mercor, which connects AI labs with domain experts for training their foundational AI models, is close to raising $350 million at a $10 billion valuation.

These 20 companies are more than just early-stage startups — they’re the architects of what’s next. And they’ll have just six minutes on the Disrupt Stage to prove it.